Zamora made his senior international debut in the friendly against Hungary last month, but a thigh injury ruled him out of contention for the opening Euro 2012 qualifier with Bulgaria.
The much-travelled 29-year-old has netted three goals in his four appearances with Fulham this season.
Hughes - who took over at Craven Cottage following Roy Hodgson's departure for Liverpool - believes there is more to come.
"When you come into a new situation you are not quite sure what you are getting, but Bobby is a top class Premier League striker," Hughes said on www.fulhamfc.com.
"Bobby is quite a package and a threat. His link-up play and team work is excellent and he is a big factor in why we have started so brightly. He is very confident in his game and he is enjoying his work."
Source: PA
Source: PA